Dr. Yong Chen is Professor of Biostatistics and Medical Informatics at Department of Biostatistics, Epidemiology, and Informatics (DBEI), and a Senior Scholar at Center for Clinical Epidemiology & Biostatistics (CCEB) at the University of Pennsylvania (Penn) Perelman School of Medicine.
He has led multiple PCORI- and NIH-funded initiatives on distributed methods and target trial emulation across multi-institutional networks. His work on real-world data has been featured by The New York Times and TIME, and one study was selected as a Top 10 Clinical Research Achievement by the Clinical Research Forum in 2026. Dr. Chen serves as a Commissioner for the Lancet Commission on Rare Diseases and is a group lead for FDA–ASA workshops on negative controls and machine learning/AI in real-world evidence. He has published over 300 papers and is an elected Fellow of the ASA, the IMS, and the American College of Medical Informatics.
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